To meet the unique nutritional needs of different people, NBI has created two versions of Osteo-K, the original Osteo-K® formula for those who need more calcium and Osteo-K Minis for those who require less calcium from a dietary supplement. If you're not sure which product is right for you, click here.
Osteo-K delivers 45 mg of MK4® (menaquinone-4) per day in divided doses to more closely match the clinical trials, plus calcium (1000 mg/day) and vitamin D (2000 IU/day).
NBI's MK4 is form of vitamin K2 derived from Orange Jasmine (Murraya paniculata) leaf geraniol extract. As a nutrient, MK4 has many positive effects on the body. Research on MK4 (45 mg/day taken in divided doses) show that it builds stronger bones and promotes healthy blood production in people with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).
Bone Support and Fracture Reduction: Two meta-analyses of clinical trials on MK4 in people with osteoporosis concluded that MK4 (45 mg/day) reduces fracture risk. One of the studies determined that MK4 (45 mg daily) can decrease the risk of vertebral fractures by 60% and all nonvertebral fractures by 76% (Cockayne S et al. Arch Intern Med. 2006;166(12):1256-1261).
A more recent study published in 2015 that evaluated 19 randomized, controlled clinical trials involving 6,759 volunteers reached the same conclusion that MK4 (45 mg/day) can reduce fractures in women with osteoporosis (Huang ZB et al. Osteoporosis International. 2015;26(3):1175-1186).
Cancer Support: The US FDA reviewed the research on MK4 (45 mg/day) for people with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). The FDA concluded that MK4 has the potential to treat these diseases, and awarded Dr. Neustadt’s company, NBI Pharmaceuticals, Inc. Orphan Drug Designation for MK4 for AML and MDS. As a dietary supplement, MK4 is not approved as a medication to diagnose, treat, prevent or cure any disease, but it can be taken as a dietary supplement to support healthy cell function.
SAFETY: Clinical trials published in medical journals document more than 7,000 people taking 45 mg daily (and higher doses) of MK4 for up to eight years without any serious side effects. The US Institutes of Medicine (IOM) states that natural vitamin K, which includes MK4, has no known “tolerable upper limit,” which means it’s considered safe even in doses much higher than that found in Osteo-K and Osteo-K Minis.
CAUTION: People taking the anticoagulant medication warfarin (Coumadin) should not take this product since vitamin K interferes with this medication.
Directions: Take two capsules twice daily with food.
120 capsules per bottle, a 30-day supply
More than 100 citations support the ingredients in Osteo-K and Osteo-K Minis for bone health, cardiovascular health and cancer support.
Gluten Free | Soy Free | Dairy Free | Corn Free
Osteo K Minis have done an excellent job of keeping my bones strong and flexible, especially as I have aged gracefully.
Thank you for your review. We're glad Osteo-K Minis is helping you.
Incredible improvements in my bone scans
I’ve been taking Osteo-K Minis for nine years to improve my bone health. My latest bone density Dexa scan (September 2021) shows a further improvement on the previous test scan (January 2019). Hip My 2019 femoral neck (hip) T-score was -1.1. In 2021 it was -0.8, a 27.3% improvement. In 2019 my total hip T-score was -0.8. In 2021 it was -0.2, a 75% improvement. Vertebral In 2019 my L4 T-score was -3.1. In 2021 it was -2.6, a 16.1% improvement. In 2019 my L3 T-score was -1.7. In 2021 it was the same (-1.7), so no change. In 2019 my L2 T-score was -1.1. In 2021 it was -0.9, an 18.2% improvement. Conclusion I no longer have osteoporosis in my hip. In my spine I still have osteoporosis, but it has improved compared to my last bone density test. Previously I was taking regular courses of Fosamax but in 2012 was ordered off that by my dentist. My doctor did not recommend another treatment. Only that I take calcium and vitamin D, but my bone density got worse. That’s when I discovered the research into MK4 and Osteo-K Minis. Once I started taking Osteo-K Minis my bones started to improve. For the last nine years I’ve taken Osteo-K and also follow a healthy diet and exercise. Overall my results are excellent! I couldn’t be happier with how Osteo-K Minis has helped me. Anyone concerned about their bones should take Osteo-K Minis. Thank you Dr Neustadt for creating Osteo-K Minis and for the research and health information on your website.
Thank you for leaving your review and sharing the details of your health. All of us here at NBI were so happy to read this and how much Osteo-K Minis has helped you.
Hip scan improved
Took this product some time ago and my hip scan came by 19% improved.
Thank you for leaving a review. I'm so glad Osteo-K Minis is helping you.
My bone density increased!
My bone density has increased significantly in only 11 months of taking Osteo K minis. I'm sure it will continue to improve.
Congratulations! Thank you for leaving a review.
I would recommend t
I appreciate Osteo K Minis deliver on time. thank you!
Thank you for your review. I'm glad you had a great ordering experience.
I’ve had osteoporosis for at least 5 years. The numbers for my spine have been worsening with each Dexa. Until my last one. After taking Osteo-K minis for only 5 months, my numbers Greatly improved on my recent Dexa. Great news. This is the only supplement my doctor wants me to take for Osteoporosis now!!!
Thank you for leaving your review and sharing your experience. It's wonderful that you saw improvement on your DEXA and that your doctor wants you to continue taking Osteo-K Minis.
Osteo K Minis
I haven't had a bone density test yet, (not due for awhile) but I'm hopeful that the results will be better than my last one after using the Osteo K Minis
Thank you for leaving your review. I hope you get the same great benefits so many others have. Please let us know how it goes when you get your next bone density scan.
It's working - gone from osteoporosis to osteopenia.
Thank you for leaving a review. That’s wonderful that your bone scan improved while taking Osteo-K Minis.
My bone scans have improved!
Thank you for leaving a review. That's wonderful that your bone density scans have improved. We're thrilled to read this!
Great experience! Wish you had discounted offers for regular clients. Expensive.
We're glad you had a great experience ordering and love the product. We do offer discounted pricing on our products. Since most people who purchase NBI supplements take them regularly, we offer quantity discounts when people buy multiple bottles. People have commented how much they like that we offer those discounts. Additionally, when we run sales people can save even more. We announce the sales in our NBI newsletter. If you want to get those sale announcements, make sure to sign up for the newsletter.