To meet the unique nutritional needs of different people, NBI has created two versions of Osteo-K, the original Osteo-K® formula for those who need more calcium and Osteo-K Minis for those who require less calcium from a dietary supplement. If you're not sure which product is right for you, click here.
Osteo-K delivers 45 mg of MK4® (menaquinone-4) per day in divided doses to more closely match the clinical trials, plus calcium (1000 mg/day) and vitamin D (2000 IU/day).
NBI's MK4 is a natural form of vitamin K2 derived from Orange Jasmine (Murraya paniculata), leaf geraniol extract. As a nutrient, MK4 has many positive effects on the body. Research on MK4 (45 mg/day taken in divided doses) show that it builds stronger bones and promotes healthy blood production in people with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).
Bone Support and Fracture Reduction: Two meta-analyses of clinical trials on MK4 in people with osteoporosis concluded that MK4 (45 mg/day) reduces fracture risk. One of the studies determined that MK4 (45 mg daily) can decrease the risk of vertebral fractures by 60% and all nonvertebral fractures by 76% (Cockayne S et al. Arch Intern Med. 2006;166(12):1256-1261).
A more recent study published in 2015 that evaluated 19 randomized, controlled clinical trials involving 6,759 volunteers reached the same conclusion that MK4 (45 mg/day) can reduce fractures in women with osteoporosis (Huang ZB et al. Osteoporosis International. 2015;26(3):1175-1186).
Cancer Support: The US FDA reviewed the research on MK4 (45 mg/day) for people with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). The FDA concluded that MK4 has the potential to treat these diseases, and awarded Dr. Neustadt’s company, NBI Pharmaceuticals, Inc. Orphan Drug Designation for MK4 for AML and MDS. As a dietary supplement, MK4 is not approved as a medication to diagnose, treat, prevent or cure any disease, but it can be taken as a dietary supplement to support healthy cell function.
SAFETY: Clinical trials published in medical journals has documented more than 7,000 people (view table summarizing these studies) taking 45 mg daily (and higher doses) of MK4 for up to eight years without any serious side effects. The US Institutes of Medicine (IOM) states that natural vitamin K, which includes MK4, has no known “tolerable upper limit,” which means it’s considered safe even in doses much higher than that found in Osteo-K and Osteo-K Minis.
CAUTION: People taking the anticoagulant medication warfarin (Coumadin) should not take this product since vitamin K interferes with this medication.
Directions: Take two capsules twice daily with food.
120 capsules per bottle, a 30-day supply
More than 100 citations support the ingredients in Osteo-K and Osteo-K Minis for bone health, cardiovascular health and cancer support.
Gluten Free | Soy Free | Dairy Free | Corn Free
The Osteo-K minis helped me move from osteoporosis to osteopenia along with a good workout 3 times a week!! My doctor was impressed. The osteoporosis occurred after a head on collision with a ***** driver in my 50’s.
So glad Osteo-K helped you! Thank you for the review and for sharing your experience.
Have been using this wonderful product since in it came on the market many years ago. I am in my mid 80's and have great bone structure and a few times that I have fallen, I have had no injuries!! Keep it coming!!
Thank you for your review. We're glad you're loving the product and it's helping you.
Fast delivery. Hard to assess the effect of this product on bone density. Hoping it will keep this 71 year old body going.
Thank you for the review. I'm glad you had a great experience ordering and that you've invited NBI into your home to help you improve your health.
After chemo for breast cancer in 2016 my DXA showed significant bone density loss in both femoral neck of hip and lumbar spine. My ND recommended OsteoK Minis because of the wonderful clinical data. I began taking in 2017 - by my repeat DXA in 2018 the femoral neck had "improved bone mineral density" and "stable osteoporosis of the lumbar spine." I cannot say enough about this product! Chemo for bc is harshest on post menopausal women so I guess it was no surprise that even with a lifetime of good habits I still developed it. Thanks to Oseto K Minis my hip is now considered to have "osteopenia" - great thing since we all know how precarious a hip fracture can be as we age. I will be using this product for good! Thank you Dr. Neustadt!
So excited for your results! Thank you for leaving a review.
A good product at a fair price.
Thank you for your review. We're glad you like the product and recognize the excellent value for the price.
First used it when I was disagnosed with osteopenia. It now seems to be under control, and if so, I know it's due mostly to Osteo-K. Many thanks.
Wonderful news! So glad Osteo-K Minis is helping. Thank you for leaving your review.
After using your product for just about a year my dexa scan showed : hip - left - return to normal and lower back stable. Cannot say enough about your product. Thank you.
Yay! Fantastic news. Thank you for sharing your experience so others can learn how the product may help them too. I'm so happy that you're bones are getting stronger and that Osteo-K Minis is helping you.
my averaged DEXA score improved by 1.2 in 11 months on this product with no other changes in diet, meds or workouts.
That's wonderful! So glad you've had such amazing results. Thank you for your review and sharing your experience.
A Great Product coupled to Great Service - What more could anyone want!
You made our day! We love how happy you are with Osteo-K Minis and our service. Our Customer Support team enjoys getting this feedback. Thank you for being a customer and taking your time to let us know how we're doing.
These are easy to swallow and have the right ingredients to foster bone health. I had been using them in the past but switched to another brand. I came back to this brand since I think they are better quality and have the best mix of ingredients.
So glad you love the product and have come back to NBI. We work hard to ensure our product are formulated and manufactured to the highest standards. Thank you for choosing NBI and being our customer.