Osteo-K
Product Description:
To meet the unique nutritional needs of different people, NBI has created two versions of Osteo-K, the original Osteo-K® formula and Osteo-K Minis (with less calcium). If you're not sure which product is right for you, click here.
Osteo-K delivers 45 mg of MK4® (menaquinone-4) per day in divided doses to more closely match the clinical trials, plus calcium (1000 mg/day) and vitamin D (2000 IU/day).
NBI's MK4 is a natural form of vitamin K2 derived from Orange Jasmine (Murraya paniculata), leaf geraniol extract. As a nutrient, MK4 has many positive effects on the body. Research on MK4 (45 mg/day taken in divided doses) show that it builds stronger bones and promotes healthy blood production in people with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).
Bone Support and Fracture Reduction: Two meta-analyses of clinical trials on MK4 in people with osteoporosis concluded that MK4 (45 mg/day) reduces fracture risk. One of the studies determined that MK4 (45 mg daily) can decrease vertebral fracture risk by 60% and all nonvertebral fractures by 76% (Cockayne S et al. Arch Intern Med. 2006;166(12):1256-1261).
A more recent study published in 2015 evaluated 19 randomized, controlled clinical trials involving 6,759 volunteers. The researchers reached the same conclusion that MK4 (45 mg/day) can reduce fractures in women with osteoporosis (Huang ZB et al. Osteoporosis International. 2015;26(3):1175-1186).
Cancer Support: The US FDA reviewed the research on MK4 (45 mg/day) for people with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). The FDA concluded that MK4 has the potential to treat these diseases, and awarded Dr. Neustadt’s company, NBI Pharmaceuticals, Inc. Orphan Drug Designation for MK4 for AML and MDS. As a dietary supplement, MK4 is not approved as a medication to diagnose, treat, prevent or cure any disease, but it can be taken as a dietary supplement to support healthy cell function.
SAFETY: Clinical trials published in medical journals document more than 7,000 people (view tables summarizing these studies) taking 45 mg daily (and higher doses) of MK4 for up to eight years without any serious side effects. The US Institutes of Medicine (IOM) states that natural vitamin K, which includes MK4, has no known “tolerable upper limit,” which means it’s considered safe even in doses much higher than that found in Osteo-K and Osteo-K Minis.
CAUTION: People taking the anticoagulant medication warfarin (Coumadin) should not take this product since vitamin K interferes with this medication.
180 capsules per bottle, a 30-day supply
References
More than 100 citations support the ingredients in Osteo-K and Osteo-K Minis for bone health, cardiovascular health and cancer support.
Gluten Free | Corn Free | Soy Free | Dairy Free