Prostate Specific Antigen (PSA)
Prostate specific antigen (PSA) is a protein produced by the cells in the prostate gland in men. PSA is elevated in patients with prostate disease such as cancer, infection, and benign prostatic hypertrophy (BPH).
PSA is used as a screening test for prostate cancer in men and used the identify the necessity for a biopsy of the prostate. The higher the PSA level, the worse the prognosis. PSA can also be used to track response to therapy.
PSA test may be indicated in men experiencing urinary symptoms, including difficulty urinating, painful urination and/or frequent urination. Research has shown that prostate cancer screening, more important than a single PSA test result is the difference between two results. That is, when the PSA number increases significantly on one PSA test compared to a previous test, additional workup may be needed.
- Prostate Specific Antigen, Total
Water: Drink plenty of water to stay well hydrated.
Medications: Take all medications as prescribed.
Dietary supplements: If you take an iron dietary supplement, do not take it the day of the blood test.
Special considerations: Avoid ejaculation for 24 hours before sample collection. Also avoid getting a digital rectal exam (DRE) and biopsy for several weeks prior to sample collection.
3-6 business days
Result turnaround times are estimates and not guaranteed. Due to factors outside of our control, such as weather, holidays, confirmation/repeat testing or equipment maintenance, our lab may require additional time to complete tests.
PSA Test (Mayo Clinic)
Bjurlin MA, Loeb S. PSA Velocity in Risk Stratification of Prostate Cancer. Rev Urol. 2013;15(4):204-206.