Dehydroepiandrosterone-sulfate (DHEA-S) is a hormone produced mostly by the adrenal glands and the brain, ovaries and testes. Sex hormones including testosterone, estrogen and progesterone are produced from DHEA-S. Symptoms of low DHEA-S include, fatigue, brain fog, decreased stamina, low libido, faster aging, muscle loss.
Alternate names: DHEA SO4, DHEAS, Dehydroepiandrosterone Sulfate, Trans Dehydroandrosterone
Methodology: Immunoassay (IA)
Fasting: Not required.
Water: Drink plenty of water to stay well hydrated.
Dietary supplements: If you are taking a biotin containing supplement be sure to stop consumption for at least 72 hours prior to sample collection.
Medications: Take all medications as prescribed.
3-5 business days
Result turnaround times are estimates and not guaranteed. Due to factors outside of our control, such as weather, holidays, confirmation/repeat testing or equipment maintenance, our lab may require additional time to complete tests.
DHEA-S naturally and normally begins to decline at age 30. In women, by the time they reach menopause, DHEA-S has decreased by 60% on average. In men between 65-75 years old, adrenal DHEA-S contributed to 40% of total androgen production. The age-related decrease may lead to osteoporosis, impaired lipid metabolism, cardiovascular disease and type II diabetes.
Samaras N, Samaras D, Frangos E, Forster A, Philippe J. A Review of Age-Related Dehydroepiandrosterone Decline and Its Association with Well-Known Geriatric Syndromes: Is Treatment Beneficial? Rejuvenation Research. 2013;16(4):285-294. doi:10.1089/rej.2013.1425.
Sorwell KG, Urbanski HF. Dehydroepiandrosterone and age-related cognitive decline. Age (Dordrecht, Netherlands). 2010;32(1):61-67. doi:10.1007/s11357-009-9113-4.